The eukaryotic initiation factor 4E (eIF4E) binds the cap structure of an mRNA as the
first step of cap dependent translation. Together with the RNA helicase eIF4A and the
scaffolding protein eIF4G, eIF4E forms the ...
The TAR DNA binding protein 43kDa (TDP-43) is a predominantly nuclear protein that is involved mainly in mRNA splicing, processing and transport. TDP-43 is also the main component of the insoluble inclusions found in neurons ...
This thesis is giving insight to the complex human-environmental linkages of global change. In order not to exceed the earth’s carrying capacity, a paradigm shift towards global sustainable development is inevitable. One ...
Nicht- oder falsch-reparierte Doppelstrangbrüche als Konsequenz einer Strahlen- bzw. Mutagenexposition können potentiell genotoxisch wirken und sich in Form von Chromosomenbrüchen und Chromosomentranslokationen im Genom ...
The present study investigates the role of Phosphoinositide 3 kinase (PI3K) pathway in the regulation of dendritic cell (DC) functions. DCs are antigen-presenting cells that provide a link between innate and adaptive ...
Environmental gradients constitute an extraordinary opportunity to study adaptation and evolution on a small spatial scale. Along such gradients abiotic and biotic factors fluctuate in space and time and allow studying the ...
ALK+ und ALK- anaplastische großzellige Lymphome (ALCL) weisen unterschiedliche miRNA-Signaturen auf, einschließlich einer niedrigen Expression von miR-146a, miR-181a und miR-26a bei ALK+ALCL. In dieser Studie wurden die ...