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Browsing by Author "Vaas, Sebastian"

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Cooperation of structurally different aryl hydrocarbon receptor agonists and beta-catenin in the regulation of CYP1A expression

Vaas, Sebastian; Kreft, Luisa; Schwarz, Michael; Braeuning, Albert (2014)
Halodifluoromethyl moieties as unconventional halogen bond donors in drug discovery and peptide design

Vaas, Sebastian (2023)
Halodifluoromethyl Moieties as Unconventional Halogen Bond Donors in Drug Discovery and Peptide Design

Vaas, Sebastian (2023-10-05)

Die in Arzneistoffen (engl. active pharmaceutical ingredients, APIs) enthaltenen Halogene Chlor, Brom und Iod (X = Cl, Br, I) sind üblicherweise kovalent an sp2-hybridisierten, aromatischen Systemen (C(sp2)-X) gebunden. ...
Synthesis of Amino Acids Bearing Halodifluoromethyl Moieties and Their Application to p53-Derived Peptides Binding to Mdm2/Mdm4

Vaas, Sebastian; Zimmermann, Markus O.; Klett, Theresa; Böckler, Frank (2023)

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