Browsing Universitätsbibliographie by Author "Hofmann, Ute"

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A pilot 'window of opportunity' neoadjuvant study of metformin in localised prostate cancer

Joshua, A. M.; Zannella, V. E.; Downes, M. R.; Bowes, B.; Hersey, K.; Koritzinsky, M.; Schwab, M.; Hofmann, U.; Evans, A.; van der Kwast, T.; Trachtenberg, J.; Finelli, A.; Fleshner, N.; Sweet, J.; Pollak, M. (2014)
A Systematic Comparison of the Impact of Inflammatory Signaling on Absorption, Distribution, Metabolism, and Excretion Gene Expression and Activity in Primary Human Hepatocytes and HepaRG Cells

Klein, Marcus; Thomas, Maria; Hofmann, Ute; Seehofer, Daniel; Damm, Georg; Zanger, Ulrich M. (2015)
A Systematic Evaluation of the Use of Physiologically Based Pharmacokinetic Modeling for Cross-Species Extrapolation

Thiel, Christoph; Schneckener, Sebastian; Krauss, Markus; Ghallab, Ahmed; Hofmann, Ute; Kanacher, Tobias; Zellmer, Sebastian; Gebhardt, Rolf; Hengstler, Jan G.; Kuepfer, Lars (2015)
Activating and Inhibitory Functions of WNT/beta-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells

Thomas, Maria; Bayha, Christine; Vetter, Silvia; Hofmann, Ute; Schwarz, Michael; Zanger, Ulrich M.; Braeuning, Albert (2015)
Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways

Weiss, Thomas S.; Lupke, Madeleine; Ibrahim, Sara; Buechler, Christa; Lorenz, Julia; Ruemmele, Petra; Hofmann, Ute; Melter, Michael; Dayoub, Rania (2017)
Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Ghallab, Ahmed; Hofmann, Ute; Sezgin, Selahaddin; Vartak, Nachiket; Hassan, Reham; Zaza, Ayham; Godoy, Patricio; Schneider, Kai Markus; Guenther, Georgia; Ahmed, Yasser A.; Abbas, Aya A.; Keitel, Verena; Kuepfer, Lars; Dooley, Steven; Lammert, Frank; Trautwein, Christian; Spiteller, Michael; Drasdo, Dirk; Hofmann, Alan F.; Jansen, Peter L. M.; Hengstler, Jan G.; Reif, Raymond (2019)
CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth

Huynh, Tony; Murray, Jayne; Flemming, Claudia L.; Kamili, Alvin; Hofmann, Ute; Cheung, Leanna; Roundhill, Elizabeth A.; Yu, Denise M. T.; Webber, Hannah T.; Schwab, Matthias; Henderson, Michelle J.; Haber, Michelle; Norris, Murray D.; Fletcher, Jamie, I (2020)
Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1)

Nies, Anne T.; Schaeffeler, Elke; van der Kuip, Heiko; Cascorbi, Ingolf; Bruhn, Oliver; Kneba, Michael; Pott, Christiane; Hofmann, Ute; Volk, Christopher; Hu, Shuiying; Baker, Sharyn D.; Sparreboom, Alex; Ruth, Peter; Koepsell, Hermann; Schwab, Matthias (2014)
Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins

Neul, Claudia; Hofmann, Ute; Schaeffeler, Elke; Winter, Stefan; Klein, Kathrin; Giacomini, Kathleen M.; Eichelbaum, Michel; Schwab, Matthias; Nies, Anne T. (2021)
Chemically induced mouse liver tumors are resistant to treatment with atorvastatin

Braeuning, Albert; Bucher, Philip; Hofmann, Ute; Buchmann, Albrecht; Schwarz, Michael (2014)
Circulating Biomarkers Instead of Genotyping to Establish Metabolizer Phenotypes

Tremmel, Roman; Hofmann, Ute; Haag, Mathias; Schaeffeler, Elke; Schwab, Matthias (2024)
Comparative analysis of 3D culture methods on human HepG2 cells

Luckert, Claudia; Schulz, Christina; Lehmann, Nadja; Thomas, Maria; Hofmann, Ute; Hammad, Seddik; Hengstler, Jan G.; Braeuning, Albert; Lampen, Alfonso; Hessel, Stefanie (2017)
Comprehensive metabolomic and lipidomic profiling of human kidney tissue: a platform comparison

Leuthold, Patrick; Schaeffeler, Elke; Winter, Stefan; Buettner, Florian; Hofmann, Ute; Muerdter, Thomas E.; Rausch, Steffen; Sonntag, Denise; Wahrheit, Judith; Fend, Falko; Hennenlotter, Joerg; Bedke, Jens; Schwab, Matthias; Haag, Mathias (2017)
Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility

Rennert, Christiane; Eplinius, Franziska; Hofmann, Ute; Johaenning, Janina; Rolfs, Franziska; Schmidt-Heck, Wolfgang; Guthke, Reinhardt; Gebhardt, Rolf; Ricken, Albert M.; Matz-Soja, Madlen (2017)
Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment

Fendt, Rebekka; Hofmann, Ute; Schneider, Annika R. P.; Schaeffeler, Elke; Burghaus, Rolf; Yilmaz, Ali; Blank, Lars Mathias; Kerb, Reinhold; Lippert, Joerg; Schlender, Jan-Frederik; Schwab, Matthias; Kuepfer, Lars (2021)
Designer thiopurine-analogues for optimised immunosuppression in inflammatory bowel diseases

Atreya, Imke; Diall, Alexandra; Dvorsky, Radovan; Atreya, Raja; Henninger, Christian; Gruen, Mathias; Hofmann, Ute; Schaeffeler, Elke; Lopez-Posadas, Rocio; Daehn, Ilse; Zenker, Stefanie; Doebroenti, Michael; Neufert, Clemens; Billmeier, Ulrike; Zundler, Sebastian; Fritz, Gerhard; Schwab, Matthias; Neurath, Markus F. (2016)
Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial

DeCensi, Andrea; Puntoni, Matteo; Gandini, Sara; Guerrieri-Gonzaga, Aliana; Johansson, Harriet Ann; Cazzaniga, Massimiliano; Pruneri, Giancarlo; Serrano, Davide; Schwab, Matthias; Hofmann, Ute; Mora, Serena; Aristarco, Valentina; Macis, Debora; Bassi, Fabio; Luini, Alberto; Lazzeroni, Matteo; Bonanni, Bernardo; Pollak, Michael N. (2014)
Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

Heintze, Tamara; Klein, Kathrin; Hofmann, Ute; Zanger, Ulrich M. (2021)
Disruption of peroxisome proliferator-activated receptor coactivator (PGC)-1 reverts key features of the neoplastic phenotype of glioma cells

Bruns, Ines; Sauer, Benedikt; Burger, Michael C.; Eriksson, Jule; Hofmann, Ute; Braun, Yannick; Harter, Patrick N.; Luger, Anna-Luisa; Ronellenfitsch, Michael W.; Steinbach, Joachim P.; Rieger, Johannes (2019)
Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Heintze, Tamara; Wilhelm, Denise; Schmidlin, Thierry; Hofmann, Ute; Zanger, Ulrich M.; Schwab, Matthias; Klein, Kathrin (2021)

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