Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

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Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

Author: Steinebach, Christian; Bricelj, Alesa; Murgai, Arunima; Sosic, Izidor; Bischof, Luca; Ng, Yuen Lam Dora; Heim, Christopher; Maiwald, Samuel; Proj, Matic; Voget, Rabea; Feller, Felix; Kosmrlj, Janez; Sapozhnikova, Valeriia; Schmidt, Annika; Zuleeg, Maximilian Rudolf; Lemnitzer, Patricia; Mertins, Philipp; Hansen, Finn K.; Guetschow, Michael; Kroenke, Jan; Hartmann, Marcus D.
Tübinger Autor(en):
Hartmann, Marcus
Published in: Journal of Medicinal Chemistry (2023), Bd. 66, H. 21, S. 14513-14543
Verlagsangabe: Washington : Amer Chemical Soc
Language: English
Full text: http://dx.doi.org/10.1021/acs.jmedchem.3c00851
ISSN: 0022-2623
DDC Classifikation: 540 - Chemistry and allied sciences
Dokumentart: Article
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