Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation

Kamaraj, Rajamanikkam; Mejdrova, Ivana; Krutakova, Maria; Smutny, Tomas; Skach, Krystof; Dohnalova, Klara; Smutna, Lucie; Nellore, Dharani Sai Sreekanth; Dusek, Jan; Chalupsky, Karel; Hricova, Jana; Kronenberger, Thales; Stahl, Aaron; Templin, Markus; Braeuning, Albert; Nencka, Radim; Pavek, Petr

dc.contributor.author	Kronenberger, Thales
dc.contributor.author	Stahl, Aaron
dc.contributor.author	Templin, Markus
dc.date.accessioned	2026-08-25T08:52:23Z
dc.date.available	2026-08-25T08:52:23Z
dc.date.issued	2025
dc.identifier.issn	0022-2623
dc.identifier.uri	http://hdl.handle.net/10900/182595
dc.language.iso	en	en
dc.publisher	Washington : Amer Chemical Soc	de_DE
dc.relation.uri	http://dx.doi.org/10.1021/acs.jmedchem.4c03134
dc.subject.ddc	540	de_DE
dc.title	Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation	de_DE
dc.type	Article	de_DE
utue.quellen.id	20251118000000_01518
utue.publikation.seiten	14271-14299	de_DE
utue.personen.roh	Kamaraj, Rajamanikkam
utue.personen.roh	Mejdrova, Ivana
utue.personen.roh	Krutakova, Maria
utue.personen.roh	Smutny, Tomas
utue.personen.roh	Skach, Krystof
utue.personen.roh	Dohnalova, Klara
utue.personen.roh	Smutna, Lucie
utue.personen.roh	Nellore, Dharani Sai Sreekanth
utue.personen.roh	Dusek, Jan
utue.personen.roh	Chalupsky, Karel
utue.personen.roh	Hricova, Jana
utue.personen.roh	Kronenberger, Thales
utue.personen.roh	Stahl, Aaron
utue.personen.roh	Templin, Markus
utue.personen.roh	Braeuning, Albert
utue.personen.roh	Nencka, Radim
utue.personen.roh	Pavek, Petr
dcterms.isPartOf.ZSTitelID	Journal of Medicinal Chemistry	de_DE
dcterms.isPartOf.ZS-Issue	14	de_DE
dcterms.isPartOf.ZS-Volume	68	de_DE
utue.fakultaet	04 Medizinische Fakultät
utue.fakultaet	07 Mathematisch-Naturwissenschaftliche Fakultät
utue.fakultaet	Sonstige