MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Bady, Pierre; Sciuscio, Davide; Diserens, Annie-Claire; Bloch, Jocelyne; van den Bent, Martin J.; Marosi, Christine; Dietrich, Pierre-Yves; Weller, Michael; Mariani, Luigi; Heppner, Frank L.; Mcdonald, David R.; Lacombe, Denis; Stupp, Roger; Delorenzi, Mauro; Hegi, Monika E.

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Author:

Bady, Pierre; Sciuscio, Davide; Diserens, Annie-Claire; Bloch, Jocelyne; van den Bent, Martin J.; Marosi, Christine; Dietrich, Pierre-Yves; Weller, Michael; Mariani, Luigi; Heppner, Frank L.; Mcdonald, David R.; Lacombe, Denis; Stupp, Roger; Delorenzi, Mauro; Hegi, Monika E.

Tübinger Autor(en):

Weller, Michael

Published in:

Acta Neuropathologica (2012), Bd. 124, H. 4, S. 547-560

Verlagsangabe:

Springer

Language:

English

Full text:

http://dx.doi.org/10.1007/s00401-012-1016-2

ISSN:

0001-6322