Browsing Universitätsbibliographie by Author "Zanger, Ulrich M."

Now showing items 1-20 of 48

Next Page >>

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

Klein, Kathrin; Tremmel, Roman; Winter, Stefan; Fehr, Sarah; Battke, Florian; Scheurenbrand, Tim; Schaeffeler, Elke; Biskup, Saskia; Schwab, Matthias; Zanger, Ulrich M. (2019)
A Systematic Comparison of the Impact of Inflammatory Signaling on Absorption, Distribution, Metabolism, and Excretion Gene Expression and Activity in Primary Human Hepatocytes and HepaRG Cells

Klein, Marcus; Thomas, Maria; Hofmann, Ute; Seehofer, Daniel; Damm, Georg; Zanger, Ulrich M. (2015)
Activating and Inhibitory Functions of WNT/beta-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells

Thomas, Maria; Bayha, Christine; Vetter, Silvia; Hofmann, Ute; Schwarz, Michael; Zanger, Ulrich M.; Braeuning, Albert (2015)
Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma

Pelle, Lucia; Cipollini, Monica; Tremmel, Roman; Romei, Cristina; Figlioli, Gisella; Gemignani, Federica; Melaiu, Ombretta; De Santi, Chiara; Barone, Elisa; Elisei, Rossella; Seiser, Eric; Innocenti, Federico; Zanger, Ulrich M.; Landi, Stefano (2016)
beta-Defensin 1 ls Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor

Klag, Thomas; Thomas, Maria; Ehmann, Dirk; Courth, Lioba; Mailaender-Sanchez, Daniela; Weiss, Thomas S.; Dayoub, Rania; Abshagen, Kerstin; Vollmar, Brigitte; Thasler, Wolfgang E.; Stange, Eduard F.; Berg, Christoph P.; Malek, Nisar P.; Zanger, Ulrich M.; Wehkamp, Jan (2018)
Clinical relevance of DPYD variants c.1679T > G, c.1236G > A/HapB3, and c.1601G > A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

Meulendijks, Didier; Henricks, Linda M.; Sonke, Gabe S.; Deenen, Maarten J.; Froehlich, Tanja K.; Amstutz, Ursula; Largiader, Carlo R.; Jennings, Barbara A.; Marinaki, Anthony M.; Sanderson, Jeremy D.; Kleibl, Zdenek; Kleiblova, Petra; Schwab, Matthias; Zanger, Ulrich M.; Palles, Claire; Tomlinson, Ian; Gross, Eva; van Kuilenburg, Andre B. P.; Punt, Cornelis J. A.; Koopman, Miriam; Beijnen, Jos H.; Cats, Annemieke; Schellens, Jan H. M. (2015)
Coordinating Role of RXR alpha in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling

Keller, Roland; Klein, Marcus; Thomas, Maria; Draeger, Andreas; Metzger, Ute; Templin, Markus F.; Joos, Thomas O.; Thasler, Wolfgang E.; Zell, Andreas; Zanger, Ulrich M. (2016)
Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression

Tremmel, Roman; Klein, Kathrin; Battke, Florian; Fehr, Sarah; Winter, Stefan; Scheurenbrand, Tim; Schaeffeler, Elke; Biskup, Saskia; Schwab, Matthias; Zanger, Ulrich M. (2020)
Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

Heintze, Tamara; Klein, Kathrin; Hofmann, Ute; Zanger, Ulrich M. (2021)
Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates

Weiss, Frederik; Hammer, Helen S.; Klein, Kathrin; Planatscher, Hannes; Zanger, Ulrich M.; Noren, Agneta; Wegler, Christine; Artursson, Per; Joos, Thomas O.; Poetz, Oliver (2018)
Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism

Crane, Alice L.; Klein, Kathrin; Zanger, Ulrich M.; Olson, James R. (2012)
Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response

Zhang, J. E.; Klein, Kathrin; Jorgensen, Andrea L.; Francis, Ben; Alfirevic, Ana; Bourgeois, Stephane; Deloukas, Panagiotis; Zanger, Ulrich M.; Pirmohamed, Munir (2017)
Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Heintze, Tamara; Wilhelm, Denise; Schmidlin, Thierry; Hofmann, Ute; Zanger, Ulrich M.; Schwab, Matthias; Klein, Kathrin (2021)
Expression Variability of Absorption, Distribution, Metabolism, Excretion-Related MicroRNAs in Human Liver: Influence of Nongenetic Factors and Association with Gene Expressions

Rieger, Jessica K.; Klein, Kathrin; Winter, Stefan; Zanger, Ulrich M. (2013)
Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody

Emond, Jean-Philippe; Labriet, Adrien; Desjardins, Sylvie; Rouleau, Michele; Villeneuve, Lyne; Hovington, Helene; Brisson, Herve; Lacombe, Louis; Simonyan, David; Caron, Patrick; Perigny, Martine; Tetu, Bernard; Fallon, John K.; Klein, Kathrin; Smith, Philip C.; Zanger, Ulrich M.; Guillemette, Chantal; Levesque, Eric (2019)
Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1

Tremmel, R.; Klein, K.; Winter, S.; Schaeffeler, E.; Zanger, U. M. (2016)
Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis

Rosmarin, Dan; Palles, Claire; Church, David; Domingo, Enric; Jones, Angela; Johnstone, Elaine; Wang, Haitao; Love, Sharon; Julier, Patrick; Scudder, Claire; Nicholson, George; Gonzalez-Neira, Anna; Martin, Miguel; Sargent, Daniel; Green, Erin; McLeod, Howard; Zanger, Ulrich M.; Schwab, Matthias; Braun, Michael; Seymour, Matthew; Thompson, Lindsay; Lacas, Benjamin; Boige, Valerie; Ribelles, Nuria; Afzal, Shoaib; Enghusen, Henrik; Jensen, Soren Astrup; Etienne-Grimaldi, Marie-Christine; Milano, Gerard; Wadelius, Mia; Glimelius, Bengt; Garmo, Hans; Gusella, Milena; Lecomte, Thierry; Laurent-Puig, Pierre; Martinez-Balibrea, Eva; Sharma, Rohini; Garcia-Foncillas, Jesus; Kleibl, Zdenek; Morel, Alain; Pignon, Jean-Pierre; Midgley, Rachel; Kerr, David; Tomlinson, Ian (2014)
Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites

Muerdter, Thomas E.; Kerb, Reinhold; Turpeinen, Miia; Schroth, Werner; Ganchev, Boian; Boehmer, Gabriele M.; Igel, Svitlana; Schaeffeler, Elke; Zanger, Ulrich; Brauch, Hiltrud; Schwab, Matthias (2012)
Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

Nies, Anne T.; Niemi, Mikko; Burk, Oliver; Winter, Stefan; Zanger, Ulrich M.; Stieger, Bruno; Schwab, Matthias; Schaeffeler, Elke (2013)
Genetics, Epigenetics, and Regulation of Drug-Metabolizing Cytochrome P450 Enzymes

Zanger, U. M.; Klein, K.; Thomas, M.; Rieger, J. K.; Tremmel, R.; Kandel, B. A.; Klein, M.; Magdy, T. (2014)

Now showing items 1-20 of 48

Next Page >>

Report a Publication

Help

Browse

All of DSpace
This Community

Browsing Universitätsbibliographie by Author "Zanger, Ulrich M."

DSpace Repository

Browsing Universitätsbibliographie by Author "Zanger, Ulrich M."

Browse

All of DSpace

This Community

My Account